As to the safety of fullerenes, scientists failed to arrive at a consensus at once. In 2004, in the U.S.A., two papers were published. They demonstrated the toxic effect of fullerene С60 derivatives on aquarium fish and water flea. This initiated a serious academic discussion and a wide range of additional investigations. With time, the error was found. The cause of animal death was not fullerene but the toxic solvent the American researchers used.

In 2005, a group of researchers headed by Prof. Fathi Moussa at the Universit? Paris Sud XI, in investigating the effect of very big doses of fullerene С60 (up to 2.5 grams per kilogram of weight) on rats, found no toxicity. After some time, Japanese researchers confirmed the results of their French counterparts.

A question offers itself: How can intake of fullerene during the lifetime affect the organism? The results of these studies were published in 2012. French researchers added 1.7 mg/kg of fullerene С60 dissolved in olive oil to the ration of rats. When conducting the experiments, the researchers assumed that if the toxic effect of fullerene will be manifested, the lifetime of rats would shorten. The experiments failed to show any toxic manifestations of the additive. Moreover, the animals on a “fullerene” diet continued to live after the control group rats had died. They lived about twice as long as rats with an ordinary lifetime. The average lifetime of rats in the control group was 22 months, whereas those on the “fullerene” diet lived for 42 months, and those on oil without fullerene lived for 26 months. Administration of fullerene in olive oil increased the average lifetime of the animals by 90 %.